Itchy blisters

Itching around a blister can be a sign that the blister is healing. Other possible causes of itchy blisters include a viral illness, such as chickenpox or shingles. Red bumps may turn into blisters that become cloudy, break, and scab over. Contact with something in the environment that causes a skin reaction. Plants such as poison ivy, oak, and sumac can cause itchy blisters. A reaction to an insect bite or sting or a spider bite also can be the causes of itchy blisters. An infection from mites that burrow in the skin can also be the cause of itchy blisters. Tiny itchy blisters occur most often in a thin line. In rare cases, do a disease that causes your body to attack your own skin, such as pemphigus or dermatitis herpetiformis. Itching can often be treated at home. Treatment for itchy blisters focuses on taking steps to decrease itching and to identify and treat the cause of the itching. It is important not to scratch the rash to prevent infection and scarring.

Best treatment

Usually, it is best to leave blisters alone. Because blisters protect the underlying skin, breaking blisters open can increase the chance of infection. Protect blisters with a bandage and cover them until they heal on their own. The liquid in the blister will be re-absorbed and the skin will flatten naturally. If a blister breaks, wash the area with soap and water, then apply a bandage. If a blister is very large or painful, your doctor may drain it and apply an antibacterial cream to prevent infection.

Other treatments

The treatment for blisters caused by eczema, infections and other diseases varies. Some cases of eczema can be treated with corticosteroid cream or pills. Herpes simplex infections and shingles sometimes are treated with antiviral medications. Antibiotic cream or pills may be given for impetigo. Chickenpox and coxsackievirus generally are left to go away on their own. The itching caused by chickenpox can be relieved with over-the-counter, anti-itch lotions, such as calamine. With medication-related erythema multiforme, the medication must be discontinued immediately. Corticosteroids sometimes may be prescribed.


Pemphigoid and pemphigus are treated with corticosteroids and/or other immunosuppressive agents. Because dermatitis herpetiformis is associated with celiac sprue, people with dermatitis herpetiformis may benefit from a diet that does not contain any gluten. Porphyria can be treated with regular removal of blood or with medications, including cholestyramine, chloroquine and beta-carotene. Some inherited skin disorders that cause blistering may respond to measures that protect the skin from trauma.

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